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Tirzepatide studies show similar findings

Ragsdale LB et al

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Rather than directly correcting pigmentation at its source, certain ingredients may influence oxidative pathways and melanin regulation processes within the body

Furthermore, the longer half-life resulting in receptor activation over 24 h would be in line with the increased HR during the diurnal and nocturnal periods reported for liraglutide and dulaglutide [24, 30]