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For the participants who finished phase 2, there was little change in severity of diarrhea (0.52 +/-0.79 at beginning, 0.57 +/- 0.79 at end) and a small increase in severity of constipation (0.61 +/- 0.89 to 0.87 +/- 1.1, not significant)

Discontinue if irritation occurs

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