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The research team found that participants with genetic makeup mimicking the effect of GLP-1 receptor agonists leads to reductions in both lean mass (whole-body fat-free mass and trunk fat-free mass) and body fat (whole-body fat mass, trunk fat percentage and body fat percentage)
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Lancet (London, England) 394(10193):121130 Gerstein HC, Lee S-F, Par G, Bethel MA, Colhoun HM, Hoover A, Lakshmanan M, Lin Y, Pirro V, Qian H-R et al (2023) Biomarker changes associated with both dulaglutide and cardiovascular events in the REWIND randomized controlled trial: a nested case-control post hoc analysis
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