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In the beginning of the year, this is always more pronounced, because each insurance changes what they're doing for coverage. Gastrointestinal side effects can also make it tough to stick with GLP-1s, says Dr
Stickel F, Kessebohm K, Weimann R, Seitz HK
Older weight-loss drugs tended to shave off only a few percentage points of body weight, and they came with tough trade-offs and quick weight rebound