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Published 2020 May 27

Cell 186 , 13371351.e1320 (2023)

Interestingly, caspase activation by the extrinsic pathway has been reported to be able to stimulate the intrinsic pathway of apoptosis, due to the cleavage of the pro-apoptotic protein Bid into a truncated form termed tBid (Schulze-osthoff et al., 1998)