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Pregnant rats given semaglutide at clinically relevant doses produced offspring with reduced growth and increased skeletal and visceral malformations
If your body still not responding ideally then your physician may opt high dose of 1mg to achieve the target goal or 2mg for better control

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& Yockey, S
GLP-1 receptors exist throughout the vascular system, and their activation may alter autoregulation of blood flow to the optic nerve head, particularly during nocturnal blood pressure dips when many NAION events occur