However, these peripheral findings should not be interpreted as direct evidence of brain-specific CAT modulation
*Correspondence: Su-Mei He, [email protected] Zhu, [email protected] Wei, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Clinical Nutrition, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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In the AMPK pathway, the level of GPX4 is downregulated due to the depletion of SIRT3, which in turn inhibits ferroptosis[107]
T2DM, Type 2 diabetes mellitus
This cellular protection supports muscle recovery and reduces prolonged inflammatory signaling that can interfere with performance and healing