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The inhibition of TECs ferroptosis can effectively ameliorate renal interstitial fibrosis and significantly reduce the expression of profibrotic factors through the inhibition of TGF-/Smad signaling

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However, excessive activation of autophagy may result in adverse effects, as the process also contributes to follicular atresia and granulosa cells death

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Following digestion of pC210 with Nde I and Sph I to remove the SSA1 coding sequence, similarly digested gliT PCR product was ligated into pC210 to create pC-GliT