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Any discussion of interactions at this stage is therefore based on pharmacological reasoning and extrapolation from related, licensed GLP-1 receptor agonists such as semaglutide (Ozempic, Wegovy) and tirzepatide

However, prolonged high doses of vitamin B12 can lead to various side effects: Anaphylactic shock: This allergic reaction to vitamin B12 is rare but very dangerous, potentially leading to death

Chemical modification of a specific inhibitor of nicotinamide N-methyltransferase to generate a membrane-permeable prodrug. Journal of Medicinal Chemistry , 61(3), 1366-1371

If you feel fatigued, numb, or foggy despite healthy habits, a B12 deficiency could be the cause

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