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The accumulation of these metabolites has been shown to inhibit -KDD activity (most likely due to -KG depletion), thereby promoting stem cell differentiation [107, 108]
Low glutathione appears in conditions of accelerated aging like diabetes and metabolic syndrome [20]
However, -oxidation yields acetyl-CoA, which enters the TCA cycle by condensation with oxaloacetate for further oxidation
C.Di FulvioM.LaufP
C., Boakye, H
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