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If you are still experiencing significant nausea, diarrhea, or vomiting at the end of a 4-week period, stay at the current dose for another 2-4 weeks

Together, these results suggest that GLP-1R activation remodels systemic and plaque-localized inflammatory and lipid-handling pathways in a manner that may directly contribute to plaque stabilization and reduced cardiovascular risk

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A provider who explains this reasoning clearly tends to leave patients with a more realistic sense of what a supervised, phased plan actually involves