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For people with hemophilia who are also managing type 2 diabetes or obesity, these drugs may be an appealing option

However, DOPAL can be detoxified by NAD(P) + -dependent aldehyde dehydrogenase (ALDH) or reduced by aldehyde/aldose reductase (ALR/AR) to form the inactive 3,4-dihydroxyphenylethanol, or further oxidized to non-toxic 3,4-dihydroxyphenylacetic acid where the aldehyde moiety is replaced by a carboxyl group [32]

This DPP-4 inhibitor is contraindicated in this patient group on the basis of the respective cardiovascular safety study that has shown a significant increase of hospitalization for heart failure as secondary endpoint in the saxagliptin arm (63, 66)

Side effects that are possible with Glutathione include hypersensitivity reaction, allergic reaction, palpitations, chills, fever, insomnia and rash

Key Features: -Supports heart health and cardiovascular function