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This medication works by slowing down the movement of food through your gut, which allows your body to absorb more water from your stools and make them firmer
1 Introduction 1.1 Relationship among gut microbiota, TMA and TMAO production, and human diseases Consolidated literature from over the last 20 years confirms the relationship between intestinal microbiota and a series of diseases ( 1.2 Biochemical mechanisms of TMA production Most of the TMA is synthesized in the intestine (colon) by the action of some anaerobic commensal gut bacteria containing choline- (or carnitine-) TMA lyase, an enzyme consisting of two units: a catalytic unit (CutC) and its activating enzyme (CutD) ( etc .), betaine, and L-carnitine and its metabolite -butyrobetaine (GBB), releasing TMA after the cleavage of the carbon (C)nitrogen (N) bond of choline/carnitine ( 1.3 Trimethylaminuria (TMAU): etiology, psychosocial impact, and incidence Trimethylaminuria (TMAU) is caused by TMA accumulation

Frequency Once weekly Instructions Inject under the skin of your stomach, thigh, or upper arm using the pre-filled KwikPen Titration Start at 2.5mg, with increases every 4 weeks up to maximum 15mg Side Effects Common Side Effects Most side effects are mild and improve as your body adjusts to the medication
If the medicine is compounded, and therefore not FDA-approved, that also needs to be disclosed
Any history of alcohol-related health problems , including liver disease, pancreatitis, gastritis, or previous attempts to reduce drinking Changes in drinking patterns since starting GLP-1 medication, whether increased or decreased consumption, or altered tolerance to alcohol Gastrointestinal symptoms and whether alcohol worsens nausea, vomiting, or other side effects Concerns about alcohol use disorder : If you're finding it difficult to control your drinking, your GP can arrange referral to specialist NHS alcohol services Your GP should provide personalised advice based on your individual circumstances, including other medications, comorbidities, and treatment goals