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Lancet Gastroenterol Hepatol 7(4):367378

Semaglutide is generally considered safe, but like all medications, it can have side effects

& Parsonnet, J

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It is not clear whether the replacement of melanocytes of the basal cell layer of the oral epithelium lost to physiological processes of apoptosis or senescence, or to mechanical, thermal, or chemical injury is the result of cell division of mature melanocytes in the basal cell layer of the oral epithelium which still retain their capacity of replication, or a result of migration from their local niche reservoirs of melanocyte stem/progenitor cells and their subsequent proliferation [6]