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One of these disorders is gigantism (at a later stage called acromegaly), where the bones of the hands, feet, and face grow too large
It acts as the ultimate electron donor for the glutaredoxin system, which activates ribonucleotide reductase (RNR) , the rate-limiting enzyme responsible for converting ribonucleotides into the deoxyribonucleotides (dNTPs) needed for DNA replication
11 (Suppl 1): S73S85
The most frequently reported side effects were mild to moderate nausea, diarrhea, and constipation
10.1002/ajmg.b.30366 18
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