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Gut 2009;58:990-7.ArticlePubMed 49
PT141 may stimulate the melanocortin system and alter sexual desire or vascular tone
People with metabolic disorders or on insulin therapy should seek medical supervision
Recent studies of isolated L-cells (95) and a L-cell derived cell line, GLUTag cells, have shown stimulation of GLP-1 secretion by glucose acting to inhibit K+ channels as in islet beta cells, by activation of the SGLT-1 transporter leading to depolarization (91), or activation of sweet taste receptors (T1R2 / T1R3) which activate Gq and PLC
The mechanism of satiety: effect of glucagon on gastric hunger contractions in man
L.HsingA.LeeK
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