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Di Iorio BR et al

Weight loss is an important component for those who are overweight or obese, but so are other aspects of self-management

Background standard-of-care at baseline included metformin for 77% of patients, insulin for 61%, and sulfonylureas for 32%

The RCTs were based across 12 countries on four continents, but involved only high- or middle-income countries, mostly Western

Overweight is often linked to consuming too many fatty foods, overeating, and digestive problems due to an imbalance in digestion and gut bacteria

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