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When epicardial adipose tissue is in excess, its potential benefits on thermoregulation and mechanical protection of the heart are countered by proinflammatory activity and with a worse haemodynamic and metabolic profile in patients with HFpEF

If you have a sluggish metabolism or mild fatty liver concerns, these shots go beyond the symptoms to address the underlying causes

Moreover, it exhibits antioxidant properties (Sahebnasagh et al., 2022), balancing hypertonicity-induced imbalances between oxygenase and antioxidant enzymes, reducing ROS production, inhibiting lipid peroxidation, preventing oxidative DNA damage, and suppressing the production of heme oxygenase-1 and cyclooxygenase-2

For weight loss, significant results are typically observed around the 28-week mark, emphasising the importance of a balanced diet and exercise in conjunction with Mounjaro therapy

But as a clinician, we're thinking of someone with overweight or obesity

Duration of intervention was 12, 26, 40 and 52 weeks in one, one, three and two studies, respectively