When the peptide binds with copper ions, it forms a biologically active complex capable of transporting copper into tissues and cells
Beyond monocytes and macrophages, other leukocytes, like the most abundant circulating and tumor-infiltrating neutrophils [174], which can cross the bloodbrain barrier [175], and T cells, essential in adaptive immunity, are considered to be instrumental in tumor elimination [176], have been leveraged for nanoparticle delivery to tumor tissues
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