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Hu ML, Rayner CK, Wu KL, et al
GH-releasing peptides (GHRPs), the first component of the GHS family, were invented, not isolated, in 1977, and are endowed with strong growth hormone releasing effects both in animals and in humans [R]
However, the expression of GPx1 has been reported to be down-regulated in thyroid cancer [44], colorectal cancer [45, 46], and gastric cancer [47], whereas GPx1 has been demonstrated to play an oncogenic role in kidney cancer [48], pancreatic cancer [49], and laryngeal squamous cell carcinoma [50]
It plays a pivotal role in protecting cells from damage caused by free radicals and oxidative stress, both of which can adversely impact skin health and accelerate the ageing process
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