They also trigger the release of insulin from the pancreas and inhibit the secretion of glucagon, a hormone that raises blood sugar levels
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They affect appetite, stomach emptying, blood sugar physiology, and weight in meaningful ways
While animal studies have shown potential risks - such as reduced fetal growth and skeletal abnormalities - human data is still emerging
In the context of male patients, clinicians should also be aware of the encouraging data that metabolic improvements via GLP-1 RAs can favorably influence male reproductive hormones and function
For employers with several Medicare eligible employees, the financial impact could be substantial over time