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Tumor cells induce platelet aggregation 64 (3) and support angiogenesis (new blood vessel formation) (4)
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It modulates the nitric oxide (NO) system in a bidirectional manner, meaning it can counteract both NO-excess states (like those caused by L-arginine or NO donors) and NO-deficiency states (such as those induced by L-NAME)
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The MC4R protein belongs to the Class A G protein-coupled receptor family, consists of 332 amino acids, and has seven transmembrane domains
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