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U-100 Syringe marks On a U-100 insulin syringe, 100 marks equal 1 mL

Comparison to Other Routes Intravenous: 100% bioavailability (by definitionthe full dose enters circulation) Subcutaneous: Likely 6090% bioavailability (depends on absorption rate) Oral: ~38% systemic bioavailability This is why some researchers hypothetically prefer injected routeshigher bioavailability means lower nominal doses are needed

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Overall, injections tend to produce the greatest average weight loss in clinical trials because they act on multiple hormone pathways