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Peptide-based weight-loss treatments such as semaglutide (Wegovy) and tirzepatide (Zepbound) are only available by prescription

In the SURMOUNT-1 trial, tirzepatide produced average weight loss of 15-22.5% of body weight over 72 weeks depending on dose

The most obvious group of people who might want to look elsewhere for their longevity concerns includes the very young

Growth hormone naturally peaks during deep sleep, and evening administration works synergistically with natural circadian rhythms

At the Endocrine Societys 2025 meeting, researchers reported that in 110 men, a 10% weight loss raised the share with normal total and free testosterone from 53% to 77% over 18 months

Psychiatry 163 , 19051917 (2006)