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The largest psychiatric meta-analysis to date 80 randomized controlled trials, over 107,000 patients also found significant improvements in restrained eating and emotional eating with GLP-1 medications compared to placebo ( Pierret et al., JAMA Psychiatry, 2025 )

Horizontal axis: Evidence strength. Vertical axis: Claim scope. Place topical skin aging and wound-care context closer to stronger evidence

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1 Its endogenous ligand is GLP-2 (GLP-2(133)), a member of the glucagon-like peptide family that also includes GLP-1 and glucagon

However, while the relative importance of enzymatic vs

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