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Thats the pathway that tells endothelial cells to produce nitric oxide, which is the signal for vasodilation, angiogenesis, and blood flow recovery

This is the mechanism behind semaglutide, tirzepatide, and every other GLP-1 agonist on the market

Up to 40% of patients fail to respond or lose response to biologics, and many in clinical remission continue to suffer from debilitating extraintestinal manifestations (Abreu et al., 2020)

Studies show benefits in experimental models of ulcers, inflammatory bowel disease, and leaky gut by modulating the gutbrainimmune axis

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