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Sample size was determined based on practical considerations, prior experience with similar phase 1 study designs, and the objective of obtaining sufficient safety and pharmacokinetic data to support dose escalation decisions
Participants may receive reimbursement for: Time Travel Other inconveniences The compensation is not intended to pressure or incentivize participation
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This means attending NHS health checks when invited (available to those aged 40 to 74), discussing blood pressure, cholesterol, and blood glucose screening with a GP, being aware of bowel cancer screening (offered to those over 60 in the UK), having conversations about prostate health from the mid-forties onward for those with risk factors, and not dismissing symptoms or delaying seeking help when something feels wrong
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