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10.1016/j.peptides.2009.01.007 71 KoyamaK.ShimabukuroM.ChenG.WangM

It also activates receptors that lead to reduced core body temperature during sleep, and may modulate orexin neuron signaling, which could counteract wakefulness

Levothyroxine is a synthetic form of thyroxine (T4) that restores normal thyroid hormone levels, regulating metabolism, energy production, and numerous physiological processes

Expert opinion on drug metabolism & toxicology 5 , 12231244, doi: 10.1517/17425250903143769 (2009)

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