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It does not indicate infection, allergic reaction, or improper medication absorption unless accompanied by warmth, spreading redness, or pus

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Serious side effects, such as thyroid cancer, gallstones, pancreatitis (inflammation of the pancreas), hypoglycemia (low blood sugar levels), acute kidney failure, rapid heartbeat, extreme nausea, vomiting, diarrhea, and severe allergic reactions, are all risks associated with these two medications

Health Canada has approved naltrexone, acamprosate, and disulfiram for treating alcohol use disorder