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The review found that oral and topical formulations demonstrate significant but variable melanin reduction with minimal side effects, while intravenous glutathione carries serious safety concerns including anaphylaxis and hepatotoxicity
For example, the antibiotic chloramphenicol can interfere with the effects of vitamin B, reducing the expected hematologic response to B therapy
Expanding upon these findings, MIA-602 has exhibited significant tumor suppression in esophageal 81 , gastric 82 , and thyroid cancers 83 , as well as pleural mesothelioma 84 , prostate cancer (both androgen-dependent and castrate-resistant forms) 85,86 , pituitary adenomas 87 , melanoma 88 , and leukemias 89