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The cost of treating obesity-related diseases has reached epic proportions and is estimated to cost $147 billion in the US alone (Finkelstein et al., 2009)

PMID 12626323

You may have read about eloralintide , an investigational medication Eli Lilly is developing that targets the amylin pathway instead of GLP-1 and showed strong weight loss in a Phase 2 trial reported in The Lancet

Second generation GLP-1 receptor agonists that were developed have more similarity with human GLP-1 and are linked to larger carrier molecules to limit renal elimination

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