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Integrated metabolomics and proteomics platforms revealed a marked increase in fatty acid oxidation-related metabolites, as well as proteome changes, in PDAC treated with GLS1 inhibitors, suggesting that treatments should target multiple metabolic pathways to overcome metabolic plasticity 112,113
Cantini G, Di Franco A, Samavat J, Forti G, Mannucci E, Luconi M
The notable cardioprotective benefits of GLP-1RAs have spurred exploration into their mechanistic actions beyond glycemic control
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According to the World Health Organisation, obesity has nearly tripled since 1975, underscoring the urgent need for effective weight management strategies
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