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Its mechanism of action appears to be partly similar to established agents such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro), but retatrutide targets three receptors at once
This leads to several effects, like slowing down gastric emptying, i.e
9 GLP-1 agonists are contraindicated during pregnancy due to safety concerns, because they restrict foetal growth when given to experimental animals
Scand J Gastroenterol 35(1):7076 Portincasa P, Wang DQH (2016) Gallstones
PMID 34304009
genetic associations with insulin were obtained from the MAGIC
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