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The standard NHS protocol for B12 deficiency typically involves hydroxocobalamin 1mg intramuscularly three times a week for two weeks (if there's no neurological involvement) or on alternate days until no further improvement (if neurological symptoms are present)

Nonetheless, converting these laboratory achievements into reliable clinical results continues to pose difficulties

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Polycythaemia Vera: Treatment with B12 can mask the diagnosis of this blood disorder, so careful monitoring is necessary if B12 is started before a complete diagnosis