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There was no biological reason found why the GLP-1s weren't as effective on prostate or pancreatic cancers.) Among patients diagnosed with NSCLC, 22% taking DPP-4 inhibitors progressed to stage IV, compared with only 10% taking GLP-1s

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Although the liver enzyme elevations across the broader danuglipron database were described as in-line with approved GLP-1 agents, the single serious case, combined with regulatory input, led Pfizer to terminate the program entirely

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