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Animals (Scientific Procedures) Act, 1986, and the National Research Councils Guide for the Care and Use of Laboratory Animals, which has been approved by the Research Ethics Committee at Damanhour University (Ref
To test this, we inhibited the cysteine/glutamate antiporter System Xc - using Imidazole Ketone Erastin (IKE), thereby limiting substrate availability for GSH synthesis ( Figure 6H )
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However, normal cells need a longer, 3-week incubation compared to the 4 days that cancer cells require
CLA
Liao et al., 2014
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