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What To Know Before Taking A GLP-1 For PCOS GLP-1s are not currently approved for the treatment of PCOS, which means that docs are currently prescribing them off-label
But this research matters because it shows how fast medicine is evolving
D.PatelS.et al (2013)
The challenge is that GLP-1 medications make you not want to eat so every meal needs to deliver high protein in a portion size your reduced appetite can handle
Br J Clin Pharmacol 2025 co-infused a GLP-1 agonist with glucagon in healthy young men (Part B, n=12, median age 24): exenatide alone +4 bpm (95% CI 26), low-dose glucagon alone +4 bpm (95% CI 17), and the two together +7 bpm (95% CI 49) at 60 min
In a field moving this fast, dismissing these signals because no randomized controlled trial exists leaves patients without options they want and need now
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