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As the core cytokine in the cytokine storm, IL-17 can stimulate endothelial cells, epithelial cells, fibroblasts or macrophages to synthesize and secrete GM-CSF, IL-1, IL-6, TNF- and other cytokines and chemokines (165)

In addition, TMAO induces several inflammatory pathways, which cause the activation of pro-inflammatory cytokines such as IL-6 and TNF- which causes chronic inflammation thereby causing plaque formation and plaque rupture leading to cardiovascular disease [71]

Calculating concentrations incorrectly results in either underdosing or overdosing

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