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Handbook of Neurosurgery 7th Edition

Discovery of an NAD(+) analogue with enhanced specificity for PARP1

Given the importance of glutamine metabolism to immune cells, including activated lymphocytes, it is crucial to determine whether blockade of glutamine metabolism in tumor cells hampers anticancer immune responses

It is being explored for its possible effects on blood vessel growth, wound healing, and cell signaling

[PMID: 10684941] PubMed record related to this compound for laboratory literature review

This research area has attracted sustained scientific attention and continues to generate active laboratory investigation