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Gross-total resection is highly recommended in nearly all cases in the literature, followed by adjuvant radiotherapy or chemotherapy in selected cases to prevent metastases, which occur in 15%42% of cases

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In addition, it has been revealed that pretreatment with lixisenatide suppressed expression of oxidative stress parameters (NO, GSH, MDA and catalase enzyme), apoptotic marker (caspase-3) and inflammatory marker (TNF-) in ischemic rat brains independent on GLP-1R mediation

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Patience is required - GHK-Cu changes gene expression , not surface chemistry