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See What ConsumerLab Found White Plains, New York, February 22, 2022 Alginate supplements have been shown to be more effective than antacids in treating heartburn, indigestion, and other symptoms of GERD (gastrointestinal esophageal reflux disease)

Small-study effects were examined via funnel plots, Eggers regression, and Beggs rank test, with trim-and-fill used as sensitivity analysis when indicated

Think of it this way: estrogen helps keep the brain's power plants running cleanly and efficiently, while GLP-1 signaling ensures that aging or damaged power plants are replaced before they become a liability

Olive oil is said to induce higher GLP-1 concentrations than butter, but the study that was cited, this one, actually showed no significant difference

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If you're achieving your goals and tolerating treatment well at 4mg or 8mg, there's no requirement to push higher