All bee products, particularly venom, and honey, have been used for centuries, and their medicinal properties have been described in holy writings such as the Bible and the Quran (Dinu et al., 2024)
Accuracy matters more than convenience at this stage
Consequently, estimates vary widelyfor example, from 10% to 80% of the adult population in North America "Hiatus hernia - Illnesses & conditions"
Studies show that weight loss with HCG is mostly because of the diet, not the HCG hormone itself
References: Kraus, D., et al
Several insulin derivatives or analogs were also reported, among them the single-chain insulin with a crosslink between the A1 and B29 residues was well-studied experimentally (152155)