The STEP 1 trial [1] demonstrated that participants receiving 2.4mg weekly semaglutide achieved an average weight loss of 14.9% of their initial body weight over 68 weeks, compared to 2.4% with placebo (Wilding et al., NEJM, 2021)
Pain location outside the pelvis can be evaluated by careful history and a body map with pain locations
As a topical cosmetic ingredient, it is present in many over-the-counter products
The sustained levels may also increase the likelihood of certain side effects, particularly joint stiffness and water retention
While research results have been mixed, many in the peptide community report meaningful improvements in sleep quality
All content on Ground Truthsits newsletters, analyses, and podcasts, are free, open-access