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In addition to prevention studies, evidence from cancer-specific and mixed-population trials has raised important considerations regarding antioxidant use during active treatment
(More information) Available evidence suggests that treatment with intravenous or oral lipoic acid may help reduce symptoms of diabetic peripheral neuropathy
In addition to iron-catalyzed free radical chain reactions, lipoxygenase (LOXs) can directly oxidize PUFAs and lipid-containing PUFAs in cell membranes, which are considered to have an essential role in ferroptosis [75, 80]
However, the CagriSema combination showed a higher odds ratio for diarrhea at 6.60 compared to semaglutide alone at 2.37