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Hayes PC et al
Song et al., 2022)
[3] In vitro experiments indicate that Ipamorelin's interaction with the Growth Hormone Secretagogue Receptor type 1a (GHS-R1a) might influence the somatotroph cells located in the anterior segment of the pituitary gland
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Ozempic is intended for use as a weight loss aid in conjunction with diet and exercise
The FDA warns that both CJC-1295 and ipamorelin carry risks of immunogenicity (triggering immune responses) and cardiovascular effects, including "increased heart rate and systemic vasodilatory reaction." One clinical trial of CJC-1295 was discontinued following a participants death, though the attending physician believed the event was "unrelated to treatment." Neither CJC-1295 nor ipamorelin is FDA-approved
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