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FOXO4-DRI vs MOTS-c: Anti-Aging Peptide Comparison Senolytic vs Mitochondrial Approaches FOXO4-DRI and MOTS-c represent two fundamentally different approaches to biological aging, targeting distinct hallmarks of the aging process

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Last reviewed: June 11, 2026 Last updated: June 11, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Riboflavin is found in dairy products, eggs, liver, enriched flour, and in minor amounts in other foods

What We Know So Far Researchers at the University of Pennsylvania Health System used electronic health records to conduct what is known as a target trial emulation a rigorous design that mimics a randomized trial using real-world patient data

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