As a more severe procedure, chronic unpredictable stress (after 5 d of unpredictable stress protocol, once daily drug application during stress procedure, open field-immobility test assessment at fourth or sixth day of medication) was used
Doctors tend to find evidence of it when they are doing liver tests or imaging in the belly area (CT scans, ultrasounds) for patients who are at risk of MASLD or for some other medical reason
The position this article takes, given those three valid critiques, is that the mechanism evidence is strong enough, the delivery evidence is biologically plausible enough, and the safety window is wide enough that the recommendation is defensible
doi.org/10.3390/antiox6040082
Apply moisturizer several times a day
Both substances interact with the medication in ways worth understanding