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Expert Opin Investig Drugs 8(12):2027-2057, 1999
Carotid arterial echography revealed significantly increased maximum intimamedia thickness (20.0220.079 mm) of carotid artery after treatment with alogliptin (25 mg/d for 24 months) indicated attenuated atherosclerosis [60]
GSH has a free electron it can donate to reactive oxygen species, such as free radicals, to neutralize them, thus preventing them from damaging cells
(Feb de 2008)
GSH is also involved as an antioxidant in the detoxification of products deriving from ROS-promoted oxidation of lipids such as malonyl dialdehyde and 4-hydroxy-2-nonenal, and probably many other products of ROS interaction with cellular components (Comporti, 1987)
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