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[9] While methionine and choline do not have well-known dangerous interactions, it is essential to inform your healthcare provider of all medications, supplements, or herbal products you are taking before starting Lipo-B injections

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BPC 157 was studied almost exclusively by the same Croatian team that created it, doing rat study after rat study, while MK-677 was the domain of the Merck Research Laboratories in New Jersey, whose scientists conducted multiple small trials in humans in the 1990s, trying to see if the drug had interesting effects on a variety of surrogate markers

Citations Andrs E et al, "The pathophysiology of elevated vitamin B12 in clinical practice." QJM, June 2013

These reports are largely anecdotal and relatively rare