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SGLT2 inhibitors can reduce natriuretic peptides leading to a reduction in ventricular pressure and distention, and both pulmonary and systemic decongestion (Mascolo et al., 2022b)

All adults had a recorded diagnosis of obesity defined as BMI of 30 kg/m 2 or higher or BMI of 27 kg/m 2 to 29.9 kg/m 2 with at least one weight-related comorbidity

Switching might make sense if you never responded well to Retatrutide in the first place, but it is not a solution for plateaus after successful weight loss

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For FY27, incremental revenues are estimated at Rs 10-20 billion from India's branded formulations market, around Rs 45 billion from regulated markets like Canada and Brazil, and Rs 5-10 billion from emerging markets

Ige, Applied and Environmental Physiology Unit, Department of Physiology, University of Ibadan, Ibadan, Nigeria